Police car

A Mercedes-driving nightclub owner, who was one of Australia's most wanted alleged crime bosses, has been netted in a major Gold Coast drug sting.

Ivan Tesic, 43, was arrested on drug trafficking charges at Sydney Domestic Airport on Friday, only hours before police raided his Surfers Paradise nightclub Club Liv.

It is alleged Tesic, who had been listed as an "extreme risk" by national law enforcement authorities, led a drug trafficking network, dealing primarily in cocaine, between Sydney and the Gold Coast.

The prominent nightclub owner was among 152 people arrested on drug-related charges over three days of raids targeting the Gold Coast's party drug scene, which concluded an 18-month operation.

Fourteen patched members and 23 associates of the Bandidos, Rebels, Finks and Lone Wolfs outlaw motorcycle gangs, were also arrested during the raids.

More than 15 kilograms of cocaine was seized, as well as 1.5 kilograms of MDMA, one kilogram of methamphetamine and six litres of methamphetamine oil, which police allege could have produced $11 million worth of cocaine, as well as $500,000 in cash.

Police also intend to restrain millions of dollars in assets, including four luxury homes in Sydney and on the Gold Coast, another $700,000 in cash, luxury cars and motorcycles, and a watch worth $500,000.

Tesic, who will be charged with drug trafficking offences under Queensland's tough anti-association laws, is a part-owner of Club Liv on Orchid Avenue, where police claim cocaine and other drugs were sold.

Among those arrested in the blitz was Jamie Pickering, owner of prominent Orchid Avenue nightclubs SinCity and Vanity.

Pickering, who reportedly owns a $250,000 yellow Ferrari with the number plates SINCITY, was arrested on Sunday and is due to face Southport Magistrates Court on Monday.

Also arrested was former Bandidos sergeant-at-arms Joshua Downey, who infamously appeared on the front page of a Gold Coast newspaper claiming: "We run this town."

Downey was arrested in Airlie Beach and faced Mackay Magistrates Court on Saturday charged with drug trafficking, where he was remanded in custody.

Regional crime co-ordinator Superintendent David Hutchinson said the sting was the "most significant covert drug operation the Gold Coast had seen".

"The operation has prevented tens of kilos of dangerous drugs hitting the streets of the Gold Coast and has removed from the community a number of high-profile drug traffickers who have basically been living the high life at the expense of our youth," he told reporters on Sunday.

Taskforce Maxima boss Mick Niland said it was a "major win for the Gold Coast community".