Police have seized guns, drugs and $400,000 in cash in a raid on the home of a Comancheros bikie gang associate in Perth and charged him with a string of offences.

Gang Crime Squad officers raided the 34-year-old man's Morley home and a Bassendean factory unit on Friday as part of investigations into drug dealing and property laundering offences.

Police said the man was an associate of the Comancheros outlaw motorcycle gang and their search warrants yielded two handguns, two rifles, a silencer, 28 grams of methylamphetamine and over $400,000 in cash.

The man appeared in the Midland Magistrates Court on Friday charged with possessing a prohibited drug with intent to supply, two counts of unlawfully possessing money, eight charges of illegally possessing firearms, ammunition and a silencer, and four charges of failing to keep firearms safe.

Police said the Proceeds of Crime Squad would freeze $2 million worth of the man's property.