Detective Acting Superintendent Mark Stringer said two senior Rebels members went to a shed in the Palmerston suburb of Yarrawonga last night and became involved in an altercation with a man there at about 10:30pm.
Another person returned to the shed and drove his vehicle towards the two Rebels, hitting one of them.
The ABC has been told the two Rebels members at the site were the Darwin chapter's sergeant at arms, and the president, and the sergeant at arms was hit.
"The outcome of this altercation resulted in one of the Rebels being struck by a vehicle and subsequently being hospitalised with some serious injuries," Acting Superintendent Stringer said.
Police are understood to be investigating the reason the two Rebels were at the site.
Detective Acting Superintendent Stringer said the man had suffered extensive injuries.
He said the person driving the vehicle and the person originally at the shed were not believed to be members of the Rebels, but were known to them.